ESTUDIO WHI, REVISTA DE MENOPAUSIA, SALUD, REVISTAS MÉDICAS. Actualidad Inmediata Debido a la importancia de esta investigación y al impacto en. WHI. Progestin. Estrogen. Tibolone. Cardiovascular disease. Tromboembolic disease . Boletín de la Asociación Española para el Estudio de la Menopausia, . Los trastornos de la menopausia pueden ser evitados y combatidos Sin embargo, recientes estudios, como el estudio WHI, han puesto en duda los beneficios.

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This was the case with the WHI, a study aimed at the rstudio prevention of cardiovascular diseases in healthy postmenopausal women.

Hum Reprod, 16pp.

It demonstrates a post-factum change in perceptions about the potential effects of HT on cognitive brain function and brain aging. Recent studies on their formation, metabolism, and biological role in health and disease.


Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: It must be emphasized that the WHI report stresses that the results do not necessarily apply to lower dosages of those drugs, to estkdio formulations of oral estrogen and progestin or to estrogens and progestins administered through the transdermal route [ 1 ].

Obst Gynecol, 87pp. Folia Clin Intern, 49pp. Maturitas, 44pp. Women’s Health Initiative Investigators. Which clinical studies provide the best evidence?

However, interim reports on women on estrogens alone did not show adverse Ehi or breast cancer crossing the predetermined safety boundaries, and this part of the trial thus continues.

Principal results from the Women’s Health Initiative controlled randomized trial. In the protocol of the study it is mentioned that women had to have a base line mammography [ 5 ]. Diabetes Care, 25whii. It must be made wbi that the concept of HRT does not mean that all postmenopausal women must be always under hormonal treatments [ 11 and 12 ]. Amer J Clin Nutr, 78pp. It seems that the recommendations of the WHI writing group are mainly focused on public rather than individual health, since they say that, even small individual risks over time, and on a population-wide basis, add up to ten’s of thousands of those serious adverse health events and becomes an important public health concern.


To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. More recent epidemiological studies continue to supply evidence that long-term postmenopausal hormone therapy may reduce the risk for CAD in healthy women.

The past, the present and the future. National Institutes of Health, Is there a menopausal medicine? Unlike HERS which showed no benefit or harm after 6.

The increased risk of breast cancer became apparent only after the fourth year of treatment. Hu FB, Grodstein F. Annals de Medicina, 87pp.

Br J Nutr, 89pp. Clinical effects of standardized soy extract in postmenopausal women: When hormone replacement therapy is not possible. Maturitas, 42pp.

In addition, the telephone-administered cognitive battery showed adequate construct validity. To reassess the need of HRT after four years of therapy and not recommend HRT for the sole purpose of preventing chronic disease, such as cardiovascular disease or osteoporosis as other alternatives are available To promote the use of additional and alternative non-hormonal strategies for maintaining health and preventing disease in symptom free women of middle age and beyond.

The incidence of side effects was really very, very small in terms of individual health. Failure of estrogen plus progestin therapy for prevention. Dietary phytoestrogens and their effect on bone: Dietary intake of phytoestrogens is associated with a favorable metabolic cardiovascular risk profile in postmenopausal US women: Thus this fixed excessive dose for older women does not necessarily reflect optimal good clinical practice and is not followed by any responsible gynaecologist.


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Soy intake and the maintenance of peak bone mass in Hong Kong Chinese women. There is no reason to avoid postmenopause hormone medication when indicated and not contra-indicated.

J Clin Endocrinol Metab, 89pp. Se continuar a navegar, consideramos que aceita o seu uso. Those data describe increased risk of an entire population, not the increased risk for individual women [ 3 ].

At the time of this report clinical gynaecologists had been unblinded to treatment assignment for The WHI is an important study. Press Conference Remarks July 9, This concept failed in this specific, large group of women studied. WHIMS-Y provided an unprecedented chance to examine the hypothesis that HT may have protective effects on cognition in younger postmenopausal women aged 50—54 years.

Editorial JAMA ; 3: Second, it must be stressed that the main goal is women’s health and not hormonal therapies. Ipriflavone in the treatment of postmenopausal osteoporosis: Differences in effects between cognitive domains suggest that more than one mechanism may be involved.

Where are we now?