Dermatol. vol no.4 supl.1 Rio de Janeiro July/Aug. Two male patients diagnosed with Zoon’s plasma cell balanitis, confirmed by biopsy, were subjected to. In , JJ Zoon first recognized balanitis circumscripta plasmacellularis (plasma cell balanitis) as an idiopathic, rare, benign penile dermatosis. Balanitis is inflammation of the glans penis. When the foreskin is also affected, it is termed Zoon’s balanitis also known as Balanitis Circumscripta Plasmacellularis or plasma cell balanitis (PCB) is Albertini JG, Holck DE, Farley MF ().

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Financial support and sponsorship Nil. J Eur Acad Dermatol Venereol. Pimecrolimus, a calcineurin inhibitor which is a homologous counterpart of tacrolimus, has also been used for treatment by Bardazzi et al 9 in two patients with good response, and by Stinco et al 10 in three cases, with different results: Zoon’s plasma cell balanitis is a chronic inflammatory disease of the genital tract of unknown etiology.

Korting GW, Theisen H. Balznitis potential for malignant change. Plasma cell orificial mucositis. Male, 37 years old, uncircumcised, was referred to the STD Clinic with a 1 year history of genital lesions and no prior treatment.

Circumcision debate Inflammations Penis disorders Theriogenology. Reports have shown therapeutic success using topical tacrolimus.

At a Glance – Lichen sclerosus versus Zoon’s balanitis

In dogsbalanoposthitis is caused by a disruption in the integumentary systemsuch as a wound or intrusion of a foreign body. Histopathology with punch biopsy of one of the lesions on the glans showed a strip of infiltrate rich in plasma cells in the papillary dermis, confirming the diagnosis of Zoon’s plasma cell balanitis Figure 2.


A report of two cases treated with pimecrolimus. Views Read Edit View history. ZB is not so common clinical entity, but very less attention has been paid in the literature regarding its etiology and management of this peculiar nonvenereal genital dermatosis. Diagnosis may include galanitis identification of the cause with the aid of a good patient history, swabs and cultures, and pathological examination of a biopsy.

Petersen CS, Thomsen K. Lichen aureus of the glans penis as an expression of Zoon’s balanitis. Circumscribed plasma cell balanoposthitis and conjunctivitis in the same patient.

Plasma cell balanitis of zoon treated with topical tacrolimus 0. YAG laser – Few studies balaniyis reported Er: Medical management [ Table 2 ] Table 2 Various medical management of Zoon’s balanitis.

Indian J Sex Transm Dis. Rubor Calor Tumor Dolor Functio laesa. Treated successfully with dapsone. Zoon’s plasma cell balanitis balanitis circumscripta plasmacellularis Diagnosis requires skin biopsy.

Photodynamic therapy for Zoon balanitis.

Histopathological examination ZB has very distinct histopathological changes affecting both epidermis and dermis. Reflectance confocal microscopy RCM is an in vivo imaging method used to obtain morphologic information about both the architecture and single cells in the epidermis and superficial dermis by Vivascope Significant improvement was noted in patient 1 after 6 weeks and after 8 weeks in patient 2.


This article provides an overview of the epidemiology, clinical presentation, histopathological features, and diagnostic criteria and diagnostic methods of ZB.

Erbium-YAG-laser treatment of balanoposthitis chronica circumscripta benigna plasmacellularis Zoon. From Wikipedia, the free encyclopedia. Zoon’s plasma cell balanitis: Zoon’s balanitis treated by circumcision. J Cosmet Laser Ther. Circumcision is the definite treatment of ZB according to the European guidelines for the management of balanoposthitis.

At a Glance – Lichen sclerosus versus Zoon’s balanitis | GPonline

An overview and role of histopathology. If clinically active, treat baalnitis topical corticosteroids, but beware atrophic changes. Diagnosis and management of premalignant penile lesions. Plasma cell balani tis of Zoon treated successfully with topical tacrolimus. Balanites; Calcineurin; Male urogenital diseases; Treatment outcome.

Balanitis – Wikipedia

Surabhi Dayal and Priyadarshini Sahu. However, further studies are required to substantiate these findings. Furthermore, a regular careful clinical and histopathological monitoring is definitely zono in the management of this complex and demanding entity. Erythroplasia of Queyrat of the glans penis on a background of Zoon’s plasma cell balanitis.